Striker Victor Osimhen is expected to start for Napoli in the first leg of their Champions League last-16 tie against Barcelona, making his first appearance for the club this year.
Napoli have never won a major European match against Barcelona drawing two and losing two while they’ve previously faced them in the round of 16 in the Champions League in 2019-20, losing 4-2 on aggregate.
Napoli’s 10 Champions League goals this season have been scored by eight different players, with only Manchester City (9) having more different scorers in this season’s group stage.
New Manager Slovakia boss Francesco Calzona who replaced Walter Mazzarri on Tuesday will lead the team for his first match since his appointment
Ahead of the game Joao Felix could return for Barca after overcoming an ankle injury to take part in training on Monday.
Gavi, Ferran Torres, Marcos Alonso and Sergi Roberto remain injured.
Barcelona striker Robert Lewandowski hasn’t scored in any of his last four Champions League appearances.
Xavi’s side are winless in their last three Champions League games against Italian opponents.
Barcelona have only won one of their last 10 away games in the knockout stages of the Champions League (D4 L5), with that victory coming against Manchester United in April 2019 (1-0).