The draws for Carabao cup quarter final have been held with Holders Liverpool taking on Premier League strugglers Southampton
Manchester United will visit Tottenham Hotspur
Arsenal host Crystal Palace in a London derby, while Newcastle United are at home to Brentford.
The quarter-final ties will take place in the week of 16 December.
It is the first time in 14 years there have been no EFL clubs in the League Cup quarter-finals.
Spurs beat Manchester City in the fourth round, while United – who beat Leicester 5-2 under interim boss Ruud van Nistelrooy – will hope to have Ruben Amorim in charge by then.
